SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.3
USERS' SCORE
Good
Based on 19 Reviews
8.4
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin E (as D-alpha tocopheryl succinate)
20.1 mg
134%
Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast-free), sodium selenite)
200 mcg
364%
Top Medical Research Studies
9
Selenium supports cholesterol management
Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation.
Study reveals selenium's potential
We investigated how selenium supplementation affects cholesterol levels and the associated molecular changes. Using Sprague-Dawley male rats, we fed them diets supplemented with selenium alongside high cholesterol for three months.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
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9
Potential atheroprotective effects of T3
Atheroprotective effects of pure tocotrienol supplementation in the treatment of rabbits with experimentally induced early and established atherosclerosis.
High relevance due to significant findings
We aimed to explore how pure tocotrienol (T3), a form of vitamin E, might help in fighting atherosclerosis, a condition often linked to high cholesterol. In our study, 30 rabbits were fed high-cholesterol diets and then divided into groups receiving different doses of T3 or a control without T3.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
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9
Selenium nanoparticles show limited effectiveness
Selenium nanoparticles inhibit the formation of atherosclerosis in apolipoprotein E deficient mice by alleviating hyperlipidemia and oxidative stress.
Moderate relevance to atherosclerosis treatment
We investigated whether selenium nanoparticles (SeNPs) could combat atherosclerosis related to high cholesterol. In our study involving apolipoprotein E deficient mice on a high-fat diet, both BSA- and chitosan-coated SeNPs showed promise in reducing atherosclerotic lesions over 12 weeks.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
Read More
Most Useful Reviews
8.8
Reduced hair loss
The ingredients are balanced, the quantity is appropriate, and the packaging is good. This product helped me avoid thyroid medication. Although the taste and smell are not pleasant, I've experienced no symptoms and repeat my order, having found hair loss reduced simply by using this effective formula, albeit at an expensive price.
Read More
9.5
Selenium deficiency corrected
Two years ago, I found I was selenium deficient. Selenium is a super antioxidant that aids thyroid hormone production, crucial for maintenance of function. I found this selenium supplement with 200 micrograms, taking one capsule daily. After two years, my selenium levels are now normal, which brings me great happiness. I highly recommend this high-quality selenium.
Read More
9.5
Improved thyroid function
I recommend this high-quality complex. Selenium is crucial for the thyroid gland, activating thyroxine. It also improves iodine absorption and protects the thyroid from free radical damage, combating hypothyroidism. With vitamin E, the absorption is significantly enhanced. I once reduced my dose of euthyrox from 100 to 50, which shows its effectiveness. The capsules are easily swallowed, and the results have been significant for me.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.3
- All Researches
9
Selenium nanoparticles show limited effectiveness
Selenium nanoparticles inhibit the formation of atherosclerosis in apolipoprotein E deficient mice by alleviating hyperlipidemia and oxidative stress.
Moderate relevance to atherosclerosis treatment
We investigated whether selenium nanoparticles (SeNPs) could combat atherosclerosis related to high cholesterol. In our study involving apolipoprotein E deficient mice on a high-fat diet, both BSA- and chitosan-coated SeNPs showed promise in reducing atherosclerotic lesions over 12 weeks.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
Read More
9
Selenium nanoparticles reduce cholesterol
Selenium nanoparticles alleviate hyperlipidemia and vascular injury in ApoE-deficient mice by regulating cholesterol metabolism and reducing oxidative stress.
Positive findings for cholesterol management
We explored the effects of selenium nanoparticles on high cholesterol by studying ApoE-deficient mice on a high-fat diet. Over eight weeks, we noted that selenium nanoparticles significantly reduced total cholesterol and triglycerides while boosting beneficial HDL levels.
Additionally, these nanoparticles improved vascular health and regulated important genes for cholesterol metabolism while enhancing antioxidant enzyme activities. However, it's important to note that while the results were promising in mice, the findings do not directly translate to humans yet.
Additionally, these nanoparticles improved vascular health and regulated important genes for cholesterol metabolism while enhancing antioxidant enzyme activities. However, it's important to note that while the results were promising in mice, the findings do not directly translate to humans yet.
Read More
9
Selenium may help cholesterol levels
Hypercholesterolemia and LDL receptor mRNA expression: modulation by selenium supplementation.
Research highlights selenium's therapeutic potential
We investigated the effects of selenium supplementation on LDL receptor activity and mRNA expression in male rats with high cholesterol. The study involved feeding the rats diets with varying selenium levels along with a high-cholesterol diet over three months.
Our results showed that while high cholesterol reduced both LDL receptor activity and mRNA expression, selenium at 1 ppm effectively improved these measures. This suggests that selenium may play a positive role in managing cholesterol levels and supporting lipid metabolism.
Our results showed that while high cholesterol reduced both LDL receptor activity and mRNA expression, selenium at 1 ppm effectively improved these measures. This suggests that selenium may play a positive role in managing cholesterol levels and supporting lipid metabolism.
Read More
9
Selenium supports cholesterol management
Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation.
Study reveals selenium's potential
We investigated how selenium supplementation affects cholesterol levels and the associated molecular changes. Using Sprague-Dawley male rats, we fed them diets supplemented with selenium alongside high cholesterol for three months.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
Read More
9
Selenium reduces cholesterol in rats
[Effect of selenium on serum, hepatic and lipoprotein lipids concentration in rats fed on a high-cholesterol diet].
Highly relevant animal study
We explored how selenium affects lipid levels in rats consuming a high-cholesterol diet over ten weeks. By comparing selenium-treated groups with control rats, we found that selenium effectively reduced triglycerides, total cholesterol, and low-density lipoprotein cholesterol.
Additionally, it inhibited liver fat accumulation. These findings suggest that selenium could play a beneficial, recuperative role against high cholesterol. However, it's important to note that this research is based on animal studies, so human applicability requires further investigation.
Additionally, it inhibited liver fat accumulation. These findings suggest that selenium could play a beneficial, recuperative role against high cholesterol. However, it's important to note that this research is based on animal studies, so human applicability requires further investigation.
Read More
User Reviews
USERS' SCORE
Good
Based on 19 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Reduced hair loss
The ingredients are balanced, the quantity is appropriate, and the packaging is good. This product helped me avoid thyroid medication. Although the taste and smell are not pleasant, I've experienced no symptoms and repeat my order, having found hair loss reduced simply by using this effective formula, albeit at an expensive price.
Read More
9.5
Selenium deficiency corrected
Two years ago, I found I was selenium deficient. Selenium is a super antioxidant that aids thyroid hormone production, crucial for maintenance of function. I found this selenium supplement with 200 micrograms, taking one capsule daily. After two years, my selenium levels are now normal, which brings me great happiness. I highly recommend this high-quality selenium.
Read More
9.5
Improved thyroid function
I recommend this high-quality complex. Selenium is crucial for the thyroid gland, activating thyroxine. It also improves iodine absorption and protects the thyroid from free radical damage, combating hypothyroidism. With vitamin E, the absorption is significantly enhanced. I once reduced my dose of euthyrox from 100 to 50, which shows its effectiveness. The capsules are easily swallowed, and the results have been significant for me.
Read More
9
Normalised cholesterol levels
Selenium is best absorbed with vitamin E, thus purchasing both together is recommended. It is essential for treating conditions like arrhythmia, coronary heart disease, hypertension, and atherosclerosis, and helps normalise fat metabolism and blood cholesterol levels. It protects blood vessels and heart muscle while reducing hypertension risk. An excellent supplement with a superb composition!
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8.8
Mitigated deficiency
I am a fan of Life Extension supplements. Selenium is essential for me to mitigate the deficiency due to hypothyroidism. The composition of this supplement is impressive, made with high-quality, Non-GMO ingredients. The pill size is perfect, reducing the need to buy this supplement monthly. The contribution of selenium significantly improves my symptoms.
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Frequently Asked Questions
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